Excitation, Conduction, and Reflection of Impulses in Isolated Bovine and Canine Cardiac Purkinje Fibers
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digitalis. L Direct effects on peripheral vascular resistance. J Clin Invest 39: 930-936 Schoener EP, Dutta S, Kohn K, Marks BH (1976) Ouabain distribution in central nervous system after intrawrebroventricular or intravenous administration. Pharmacologist 18 (2): 168 Schwartz PJ, Stone HL (1977) Tonic influence of the sympathetic nervous system on myocardial reactive hyperemia and on coronary blood flow distribution in dogs. Circ Res 41: 5157 Somberg JC, Smith TW (1979) Localization of the neurally mediated arrhythmogenic properties of digitalis. Science 204: 321-323 Somberg JC, Rifiler T, Smith TW (1978) Neural factors in digitalis toxicity: Protective effect of C-l spinal cord transection Am J Physiol 235: H531-H536 Somberg JC, Mudge GH Jr, Risler T, Smith TW (1980) Neurally mediated augmentation of the arrhythmogenic properties of highly polar cardiac glycosides. Am J Physiol 238: H202-H208 Stark JJ, Sanders CA, Powell WJ Jr (1972) Neurally mediated and direct effects of acetylstrophanthidine on canine skeletal muscle vascular resistance. Circ Res 30: 274-282 Taber E (1961) The cytoarchitecture of the brainstem of the cat. J Comp Neurol 116: 27-52 Vatner SF, Higgins CB, Franklin D, Braunwald E (1971) Effects of a digitalis glycoside on coronary and systemic dynamics in conscious dogs. Circ Res 18: 470-479 Williams MH Jr, Zohman LR, Rattier AL < 1958) Hemodynamic effects of cardiac glycosides on normal human subjects during rest and exercise. J Appl Physiol 13: 417^421
منابع مشابه
Slow conduction and reentry in the ventricular conducting system. II. Single and sustained circus movement in networks of canine and bovine Purkinje fibers.
Closed loops of fibers of the ventricular conducting system of canine or bovine hearts were used to study circus movement of excitation. Action potentials were recorded at three sites with intracellular microelectrodes. Discrete segments were depressed by application of K-rich agar or the entire loop was depressed by modified Tyrode's solution containing 15—17 DIM K and 1 to 5 X 10~M epinephrin...
متن کاملExcitation, conduction, and reflection of impulses in isolated bovine and serum cardiac purkinje fibers.
When an impulse arrives at an area of impaired conductivity, a slowly rising electrotonic potential may bring the distal tissue to threshold after a delay imposed by the passive electrical properties of the system and by the time-dependent changes of these properties during diastole. This phenomenon can be demonstrated in Purkinje strands in which an area of depressed conductivity has been indu...
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Activation of cardiac muscle is mediated by the His-Purkinje system, a discrete pathway containing fast-conducting cells (Purkinje fibers) which coordinate the spread of excitation from the atrioventricular node (AV node) to ventricular myocardium [1]. Although pathologies of this specialized conduction system are common in humans, especially among the elderly [2], their molecular bases have no...
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• The relationship between the functional refractory periods of the specialized cardiac conduction system and of the ventricular muscle is of major importance in the genesis of ventricular fibrillation by a single premature beat arising in the specialized conducting system. Wiggers and Wegria demonstrated that premature ventricular excitation must occur in late systole during the inscription of...
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on the electrophysiological properties of normal Purkinje fibers and those surviving acute myocardial infarction (abstr). FedProc33:476 Schmitt FO, Erlanger J (1928-1929) Directional differences in the conduction of the impulse through heart muscle and their possible relation to extrasystolic and fibrillary contractions. Am J Physiol 87: 326-347 Singh BN, Vaughan-Williams EM (1971) Effect of al...
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تاریخ انتشار 2005